Parkinson's disease (PD) is a common neurodegenerative disease in the central nervous system, of which the pathogenesis remains unclear to this day.

帕金森病是一种常见的中枢神经系统退行性疾病，引起帕金森病的发病机制至今尚未明确。

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Objective: To study the relation among cognitive dysfunction, depression and leukoaraiosis (LA) in patients with Parkinson's disease (PD).

目的：探讨帕金森病（PD）患者的认知功能障碍与抑郁和脑白质疏松症（LA）的关系。

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Parkinson's disease (PD) is characterized by striatal dopamine depletion, especially in the posterior putamen.

帕金森病(PD)的特点是纹状体多巴胺耗竭，尤其是在后壳核。

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