This is also an expression used to show a feeling like surprise or disappointment.

VOA: special.2010.02.07

Disappointment number two, once there is a legitimate government based on consent, the only limits for Locke are limits on arbitrary takings of life or of liberty or of property.

失望的第二点，一旦经过同意建立合法政府后，对洛克来说它唯一的限制,就是不能肆意夺取生命或自由或财产。

耶鲁公开课 - 公正课程节选

In a statement,U.N.Secretary-General Ban Ki-moon expressed his "deep disappointment" with the verdict and said he "strongly deplores" the decision.

VOA: standard.2009.08.11

"It's a profound disappointment to see no sign of leadership coming from President Jacob Zuma,".

VOA: standard.2009.07.06

Haven't hit it yet so I've got to hit it next time. If I wasn't in the final it would have been a huge disappointment.

VOA: standard.2009.08.22

Senate Republican leader Mitch McConnell of Kentucky expressed his disappointment with Specter's decision, saying it could undermine Republicans' ability to put a check on the Democratic majority.

VOA: standard.2009.04.28

"There's quite a bit of concern and disappointment in President Obama, in the sense that Israel sort of under attack on all of these settlement issues, on Jerusalem,"

VOA: standard.2009.08.29