She was pierced to the heart with guilt.

她万般愧疚，心如刀割。

《牛津词典》

The cold pierced me to the heart.

我冷得钻心。

《新英汉大辞典》

This radiance pierced in a moment through the folds of sadness and despondency which had accumulated over my heart, and flooded it with this universal light.

这光明立刻穿透了累积在我心头的重重叠叠的悲戚和沮丧，以这种无处不在的光亮充溢着我的心。

youdao

Mr Wallace was shot in the lower back and the bullet then pierced his heart.

BBC: Islington flats double shooting: Men 'killed in debt row'

There was something vulnerable and uncertain in her eyes now, and it pierced his heart.

NEWYORKER: The Proxy Marriage

Its tail, venom-coated and serrated, pierced his chest and stopped his heart.

ECONOMIST: Steve Irwin