Arnsten said that the aging prefrontal cortex appears to accumulate excessive levels of a signaling molecule called cAMP, which can open ion channels and weaken prefrontal neuronal firing.
Arnsten认为,衰老的前额叶皮层中积累了过多的信号化学分子,称为环腺苷酸(Camp),它能打开离子通道,从而削弱前额叶皮层中神经元放电的频率。
JNK signaling transduction pathway plays a vivtal role in the neuronal apoptosis.
JNK信号转导途径参与神经元凋亡。
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