Objective To observe and analyse the dynamic changes of engraftment status after transplantation of mixed umbilical cord blood from two units HLA one locus mismatched.

目的动态观察分析两份HLA不全相合异基因混合脐血移植后的植入状态。

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Objective To explore the efficiency and safety of HLA partially mismatched peripheral blood stem cell transplantation (PBSCT) for treatment of acute leukemia.

目的探讨HLA半相合外周血造血干细胞移植(PBSCT)急性白血病的疗效及安全性。

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Methods: In this pilot study, 58 patients, 33 with high-risk or advanced leukemia, were transplanted with cells from an HLA-haploidentical family donor with at least 1 of 6 loci mismatched.

方法：5 8例血液恶性肿瘤患者，33例为高危或难治复发白血病，接受了至少一个HLA位点不合的家庭供者造血干细胞移植。

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