Methods The clinical features and laboratory findings in 46 SLE patients with CNS involvement were compared with 152 SLE patients without CNS disease.

方法对46例并发cns病变的SLE患者进行回顾性分析，并与152例无cns病变患者做对照。

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Objective To estimate the risk factors in patients with systemic lupus erythematosus (SLE) developing central nervous system (CNS) disease.

目的探讨系统性红斑狼疮（SLE）并发中枢神经系统（CNS）病变的危险因素。

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NP-SLE patients with local CNS involvements showed mainly the damage of blood brain barrier(BBB) .

相反，局限性CNS受损患者主要表现为血脑屏障（BBB）破坏。

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