Objective To explore the effect of thrombin (TB) on the blood brain barrier(BBB) permeability and its possible mechanism.

目的探讨凝血酶（TB）对血脑屏障通透性的影响及其可能机制。

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The increase of blood-brain barrier (BBB) permeability is a key link in causing the pathological changes in vasogenic brain edema and inflammatory reaction.

血脑屏障通透性增高是造成血管源性脑水肿和炎症反应等病理学变化的主要环节。

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Objective To study the change in blood-brain barrier (BBB) permeability in dog with craniocerebral gunshot injury and its significance.

目的探讨犬脑枪弹伤后血脑屏障(BBB)通透性改变及意义。

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