Conclusions: Tripterine has noticeable protective effects on TNBS-induced colitis in rats, suppression of proinflammatory cytokines may be one of its main mechanisms.

CONCLUSION Triptolide content in Radix Tripterygii is not constant during its storage.

METHOD HPLC gradient elution method was used with methanol-water as the mobile phase to determine the contents of triptolide in its root, branch and leaf at different periods of its storage.