OBJECTIVE: to comparison the methods of bed coating and automatic bed coating granulator preparation of pellets.
2
外层通过包衣锅包裹10%羟丙甲纤维素（K15M）制备黏附层；
The outer adhesive spheres were prepared by using coated pot with 10 percent HPMC (K15M).
3
方法粉末直接压片法制备含渗透活性物质的片芯，滚转包衣锅法分别包溶胀层和控释衣层。
Methods Core tablets containing osmotic active agent were prepared by direct compression and spray coated with swelling layer and semipermeable membrane subsequently.
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