The cyclization reactions of carbodiimide 14 with chiral amide ethyl ester was firstly studied. The results showed that the carbodiimide 14 reacted quickly with amide ethyl ester at room temperature.
The Tour de France’s organisers this year banned one leading team with a poor drug record and did not relent even when its best rider won the Giro d’Italia, another important race, in May.