Loneliness and melancholy can be severely debilitating in life, often generating incapacities for positive action and deep psychological depressions that sometimes lead to suicide;

孤独和忧郁在生活中可能让人软弱，往往导致人无法采取积极行动，陷入严重的精神沮丧，有时甚至导致自杀；

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Loneliness and melancholy can be severely debilitating in life, often generating incapacities for positive action and deep psychological depressions that sometimes lead to suicide;

孤独和忧郁在生活中可能让人软弱，往往导致人无法采取积极行动，陷入严重的精神沮丧，有时甚至导致自杀；

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