• The retrovirus carrying IL-18 gene was used to infect murine liver cancer cell MM45T.

    包装成逆转录病毒,感染小鼠肝癌细胞MM 45t。

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  • To explore the effects of IL-18 gene transfection on the proliferation of C6 glioma cell.

    探讨IL-18基因转染大鼠C6胶质瘤细胞生长特性影响

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  • Objective To investigate the serum level of interleukin IL-18 in nasopharyngeal carcinoma.

    目的探讨血清白介素- 18变化鼻咽癌的关系。

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  • Objective: it is to study the role of IL-18 in the pathogenesis of ulcerative colitis (UC).

    前言:目的:探讨IL - 18溃疡性结肠炎(U C)发病中的作用

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  • It has been demonstrated that IL-18 exists in cells of human, mammal and some kinds of birds.

    目前分子水平上已经证明哺乳动物某些鸟类中都有IL-18存在

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  • Curcumin inhabited expression of IL-18 to inhabite the proliferation of vascular smooth muscle cells.

    姜黄素抑制IL-18血管损伤后表达,抑制平滑肌增殖

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  • Interleukin-18 (IL-18) is a pro-inflammatory factor, and adipose tissue is one of its important sources.

    白细胞介素18 (IL - 18)一种前炎性因子脂肪组织重要来源之一

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  • Results: IL-12 and IL-18 induced prominent spleen deficiency syndrome similar with that induced by reserpine.

    结果IL - 12IL - 18引起明显脾虚的表现,利血平制作脾虚动物模型组相似

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  • Objective: To explore the expression of IL-18 and clinical significance in patients with lupus nephritis (LN).

    前言:目的:探讨i L - 18狼疮肾炎(LN)患者血清中的表达临床意义

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  • Objective To measure the serum level of interleukin-18(IL-18) in patients with chronic myelocytic leukemia (CML).

    目的检测慢性粒细胞白血病CML患者血清IL-18水平

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  • Results The serum level of IL-18 in tubercular pleurisy sufferer was significant higher than tha tin healthy group.

    结果结核胸膜炎患者血清IL 18水平显著高于健康对照组。

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  • Results: The D-Gal-treated rats significantly experienced a dynamic escalation of ALT, AST and IL-18 levels(P<0.05).

    结果:D-氨基半乳糖造模后,两组大血清ALT,AST匀浆IL-18值呈动态升高(P<0.05)。

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  • A weak anion exchange column was prepared and a separation method of interleukin-18 (IL-18) was developed on the column.

    制备阴离子交换整体,并建立了白介素18柱上分离纯化方法

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  • Objective To explore the effect of interleukin-18(IL-18) interference on the acute immunized hepatonecrosis animal model.

    目的探讨白细胞介素IL18 抗体干预,了解IL 18 抗体急性免疫性肝坏死动物模型的影响。

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  • Therefore, IL-18 should be seen as a unique molecule that constitutes a critical link between innate and adaptive immunity.

    因此IL - 18联系机体天然免疫获得性免疫的关键活性分子。

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  • Methods The plasma IL-18 in 36 ITP patients and 36 normal controls were detected by enzyme linked immunosorbent assay (ELISA).

    方法免疫吸附测定(ELISA)测定血浆IL - 18对36例itp患者正常对照组血浆IL - 18的水平进行分析。

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  • Objective: to investigate whether high mobility group box chromosomal protein 1 (HMGB1) can activate macrophages to secrete IL-18.

    目的探讨迁移率蛋白1 (HMGB1)能否激活巨噬细胞表达IL - 18及其受体。

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  • Methods An enzyme-linked immunosorbent assay(ELISA)was utilized to detect the levels of IL-18, VEGF in serum of 75 patients with HSP.

    方法采用固相酶免疫分析法检测75例过敏性紫癜患者血清IL-18VEGF水平

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  • In recent years studies, it has been shown that IL-18 participated in the genesis of RA, which has become a new hot spot of RA study.

    近年发现,白细胞介素- 18作用于RA发病多个参与因素,成为研究RA的热点

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  • Methods:We use ELISA and Immunohisto-chemistry to observe the level of IL-8 produced and released by SFs stimulated by IL-18 and triptolide.

    方法利用ELISA免疫组织化学法检测雷公藤甲素IL-18刺激滑膜成纤维细胞合成、释放IL-8的水平

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  • Conclusion the decline of serum level of IL-18 showed lamivudine may regulate the function of immunity and alleviate soakage of inflammation cell in liver.

    结论拉米夫定治疗il - 18水平下降,提示拉米夫定调节免疫功能减轻肝脏炎症细胞浸润

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  • Conclusion: the immune status is low in gastric cancer tissue and it can be conjectured that this phenomenon relates to the deficiency of 4-1bbl and IL-18.

    结论胃癌组织内处于低免疫状态推测肿瘤细胞免疫逃逸现象可能与4 - 1bblIL - 18缺乏有关。

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  • Some virus genome of vaccinia subgenus in poxvirus encoded IL-18BP gene, which can block IL-18 activity but no sequence similarity to membrane IL-18 receptors.

    从羊病毒基因组中寻找扩增羊白细胞介素-18结合蛋白(IL-18BP)基因

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  • CONCLUSION the level of IL-18 increases obviously on the 1st day of ACI onset and gradually decreases with the extended course of disease and time of treatment.

    结论:白细胞介素18水平发生急性脑梗死第1天时明显升高,随发病治疗时间的延长,其水平逐渐下降

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  • Objective To explore potential synergetic effects of interleukin-2 (IL-2) with IL-18 on induction of natural killer (NK) cell activity against myeloma cells in vitro.

    目的研究白细胞介素- 2 (IL - 2)白细胞介素- 18 (IL - 18)诱导自然杀伤(NK)细胞活化和抗骨髓瘤细胞活性协同作用

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  • Through the analysis of the software, it could be found that the secondary structure of IL-18 mature peptide has almost unchanged after fusion and remain its bioactivity.

    相应氨基酸序列软件分析,并il - 18成熟肽单独的分析结果相比较,发现二级结构水平几乎没有变化融合过程未影响IL - 18活性

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  • Recently, elevated IL-18 levels were found in serum from some leukemia patients, especially those with acute lymphocytic leukemia (all) and chronic myeloid leukemia (CML).

    近来研究发现急性淋巴细胞白血病(all)慢性粒细胞白血病(CML)患者血清il - 18水平高于正常人。

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  • Objective to investigate the changes of interleukin 18 (IL-18) levels in serum in patients with systemic lupus erythematosus (SLE) and its relationship with the activity of SLE.

    目的探讨白细胞介素18 (IL - 18)系统性红斑狼疮(SLE)患者血清中的水平变化及其SLE活动性关系

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  • To study rudimentarily the role of IL-18 in acute immunity hepatic injury, and the important of blocking cascade reaction of cytokines by exerting IL-18 antibody in early stage.

    通过动物实验,初步探讨IL-18急性免疫性损伤中的意义,早期使用IL-18抗体及时阻断细胞因子级联反应保护肝组织重要性

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  • Objective To detect the clinical significance of changes of serum cyclooxygenase-2 (COX-2) activity and interleukin-18 (IL-18) in patients with T2DM diagnosed by the first time.

    目的探讨初发2型糖尿病患者外周血中环氧化酶2(COX-2活性白介素18IL-18)含量变化临床意义

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