• Receptor tyrosine kinases (RTK), G protein-coupled receptors (GPCR) and ion channel receptors are main cell surface receptors.

    酪氨酸激酶型受体G蛋白偶联受体离子通道型受体细胞表面三类主要受体。

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  • G Protein-coupled receptors are a group of drug targets with important physiological functions and of pathological significance.

    G蛋白偶受体具有重要生理功能病理意义,已成为一类重要的药物靶点

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  • With more than 300 members, the G protein-coupled receptors constitute the largest family of proteins found in the membranes of cells.

    蛋白受体家族成员超过300种,它们构成细胞膜最大蛋白质家族

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  • G protein-coupled receptors play a critical role in heart disease, blood pressure regulation, inflammation and psychological disorders.

    蛋白受体心脏病血压调节炎症心理疾病中扮演关键角色

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  • The vast majority of these G protein-coupled receptors respond to hormones and neurotransmitters. They are not naturally abundant and tend to be structurally unstable.

    这类G蛋白偶受体中的绝大部分激素神经递质有反应它们自然中并不丰富在结构上趋于不稳定。

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  • The molecule is part of a large family of proteins called G-protein coupled receptors (GPCRs).

    一分子属于名为“G蛋白伴随受体蛋白家族

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  • The insect odorant receptors, as other odorant receptors from nematoid to human, have long been perceived to be G-protein-coupled receptors(GPCR).

    昆虫气味受体长久以来认为一种G蛋白偶联受体,遵循线虫人类的通用模式。

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  • G-protein Coupled Receptors (GPCRs) belong to one of the largest superfamilies of membrane proteins and are important targets for drug design.

    蛋白偶联受体属于蛋白大家族药物设计中起着很重要的作用。

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  • Lysophosphatidic acid (LPA) is a bioactive phospholipid mediator, which elicits a variety of biological functions mainly, through G-protein coupled receptors.

    溶血磷脂(LPA)一种生物活性磷脂介质主要通过G蛋白偶联受体发挥多种生物学功能

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  • CCR5, a membrane protein on cell surface, is a member of the G protein-coupled receptor superfamily and one of the major co-receptors for HIV-1infection.

    CCR5为细胞膜蛋白,属于G蛋白偶联受体家族成员HIV - 1入侵机体细胞的主要辅助受体之一。

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  • G-protein coupled receptors do not have ion channels as part of their structure; they affect channels by activation of intermediate molecules called G proteins.

    蛋白耦联受体本身并不具备离子通道它们通过G蛋白分子介导通道激活

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  • STAT proteins are activated by G-protein coupled receptors, while it has not been reported whether CCK receptors, a kind of G-protein coupled receptors, can activate JAK/STAT pathway.

    STAT蛋白可被G 蛋白偶联受体激活CCK 受体作为G 蛋白偶联受体,是否JAK/STAT通路具有直接激活作用,尚未见报道

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  • The molecular structure of adrenoceptor fits common model of G protein coupled receptors on membrane surface.

    肾上腺受体分子结构符合G蛋白表面受体一般特征。

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  • Also, disclosed are diagnostic methods for detecting a mutation in the G-protein coupled receptor nucleic acid sequences and an altered level of the soluble form of the receptors.

    发明还公开了检测G蛋白偶受体核酸序列中的突变诊断方法以及检测受体可溶形式改变水平的诊断方法。

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  • Disclosed herein are methods for enabling or improving functional assays of G-protein coupled receptors through the use of co-expression of helper genes.

    发明公开了通过应用辅助基因表达来实现改进G蛋白偶受体功能分析方法

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  • In 1990s, molecular biological approach has led to a series of cloning and functional expression of ligand-gated P2X receptors and G-protein coupled P2Y receptors.

    90年代采用分子生物学手段一系列配体门控P2 X受体G蛋白耦联的P 2y受体被克隆功能表达

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  • In 1990s, molecular biological approach has led to a series of cloning and functional expression of ligand-gated P2X receptors and G-protein coupled P2Y receptors.

    90年代采用分子生物学手段一系列配体门控P2 X受体G蛋白耦联的P 2y受体被克隆功能表达

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