Pathologists have even found tiny deposits of prostate cancer cells in men in their 20s.
When the mice were kept calm and free of stress, the drug destroyed prostate cancer cells and inhibited tumor growth.
Another approach, now being tested by Millennium Pharmaceuticals and, separately, by Medarex, is to develop smart antibodies that help destroy prostate cancer cells.
One model used mice that were implanted with human prostate cancer cells and treated with a drug that is currently in clinical trial for prostate cancer treatment.
Millennium's drug, now in early human trials, homes in on prostate cancer cells and aims to obliterate them with a precise dose of toxic chemotherapy while leaving surrounding tissue untouched.
They include compounds that block bad genes responsible for spreading cancer into the bones, chemicals that prompt prostate cancer cells to destroy themselves and vaccines that train the body's killer T-cells to seek and destroy tumor cells.
They include compounds that block bad genes responsible for spreading cancer into the bones, chemicals that prompt prostate cancer cells to destroy themselves and vaccines that train the body's killer T cells to seek and destroy tumor cells.
These are part of the immune system and, if suitably treated with a substance called a fusion protein, can be used to make prostate-cancer cells vulnerable to immune attack.
And radiotherapy technology advances mean that far higher doses can be targeted more precisely on the prostate, killing more cancer cells with fewer treatments.
By combining the Gleason score (determined by a pathologist examining cancer cells under a microscope), the clinical stage (determined by a careful prostate exam and various scans) and the PSA level, we can stratify patients into "low, " "intermediate" and "high" risk categories.
WSJ: Are PSA Tests a Good Idea for Screening Men for Prostate Cancer?
应用推荐