• They work by inhibiting prostaglandin, a hormone-like substance that plays a part in signalling pain to the brain.

    BBC: Pregnant women warned off painkillers

  • The main ingredient in each, alprostadil, is a synthetic version of the blood vessel dilator prostaglandin E-1, which also is found in semen.

    FORBES: Health

  • Any potential effects of the prostaglandin drug might not show up.

    FORBES: Magazine Article

  • Merck said Zioptan is the first preservative-free prostaglandin analog ophthalmic solution.

    WSJ: New Drug Approved to Treat Eye Condition

  • Both Steve Nissen and Allen Taylor say little is known about the long-term effects of its flushing-blocker, which works by blocking a cell receptor called prostaglandin D2.

    FORBES: Magazine Article

  • One possible inflammation target is a fat called prostaglandin E2.

    FORBES: Pharma Prophet

  • If drug developers could better target their inhibitors farther down the prostaglandin chain, they might produce powerful drugs that could fight pain and avoid unknown, possibly fatal, side effects.

    FORBES: Magazine Article

  • Another possible drug target is the prostaglandin thromboxane.

    FORBES

  • This research could also lead to urine and blood tests that would measure prostaglandin levels and predict those who would benefit from drugs like Celebrex and those for whom the drugs might cause heart attacks.

    FORBES: Pharma Prophet

  • This prostaglandin-producing enzyme is called cyclo-oxygenase (COX).

    FORBES: Magazine Article

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