Turns out receptors work together in an amazingly sophisticated "combinatorial code" to identify particular odors.
Over dinner Schreibershared with Adams his disdain for combinatorial chemistry, the high-speed fabrication of synthetic molecules.
Then, in a process called combinatorial biosynthesis, they change the genes too, leading to new drugs.
After screening dredges up a promising drug candidate, combinatorial chemistry takes a hand.
It is trying combinatorial techniques to search for other complex materials, such as catalysts for the chemical industry.
The combinatorial method, if it works, should make it a lot less painstaking, and a lot more profitable.
Combinatorial chemistry elaborates lead drugs (such as the one that led to Lillys antimigraine drug) into entire families of related compounds.
Whether combinatorial chemistry will have as many uses outside the realm of drugs as in it is not yet clear.
Could combinatorial publishing inspire more cheating and less genuine thinking by students and others who are merely completing research reports?
The researchers' combinatorial technique was not to make a separate cell on the wafer for each combination of precursors, as Dr Xiang did.
Mario Geysen, now a senior research scientist at Glaxo Wellcome, pioneered combinatorial chemistry back in 1982 when he was at the Commonwealth Serum Laboratories in Melbourne, Australia.
Circa is a sort-of news publishing combinatorial engine, powered by editors.
Villhauer took advantage of a new rapid-fire method called "combinatorial chemistry, " which allowed him to brew hundreds of compounds simultaneously instead of one at a time.
How does combinatorial publishing protect the copyrights of original material?
And the combinatorial part explains how innovation begets innovation.
Instead of making drugs, they would use the high-tech tools of gene chips, high-throughput screening, combinatorial chemistry (the rapid mixing and matching of chemicals) and bioinformatics (software that analyzes data)--to develop entirely different compounds.
Craig Venter, who mapped the genome back in 1995, talked about his latest project: ushering in the "Jurassic Park" era of combinatorial genomics, where scientists will create life by typing out DNA. He predicts his team will be able to produce a single-cell eurkaryote--and eventually gasoline--in the lab from cellular building blocks within ten years.
应用推荐