It is important for each individual to consider carefully the possible risks and benefits of a clinical study before making a decision to participate.

让每个患者在决定参与前都清楚地认识到临床研究可能的风险和利益是重要的。

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With all those mechanisms, a reconstituted object loses its referential identity, and you have to consider carefully whether your singleton is still a singleton.

使用这些序列化机制时，被重建的对象将失去原对象的相关标识，所有必须特别注意单例对象是否依然是单例的。

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However, if you're running a professional business site, you have to consider carefully if you want to detract from your message and professionalism with advertising.

不过如果你运行的是一个专业商务网站，你想减少内容消息并专业化广告，你就必须仔细考虑了。

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"I urge people to consider carefully the implications of releasing a lantern, " she added.

BBC: Wales' chief vet backs warnings over sky lanterns

"These are lessons the government will need to consider carefully as it reviews its plans for the prison estate".

BBC: Merged Isle of Wight prison criticised in report

We not only need to consider carefully the individual relationships we form with young people but also those between young people and the wider community.

BBC: NEWS | Programmes | Panorama | The system needs to be challenged