The most important thing is not to admit defeat until you really have to.

最重要的事就是非到不得已不要认输。

《柯林斯英汉双解大词典》

Perhaps the most important lesson to be learned is that you simply cannot please everyone.

或许应吸取的最重要的教训是你不可能取悦每一个人。

《柯林斯英汉双解大词典》

I have to reiterate: The most important thing you need to do to lose body fat is to stop your sugar and cereal intake and keep your carbohydrate intake low.

我必须要重申一下：要想减掉体内脂肪，你要做的最重要的事就是停止糖和谷物的摄取，并保持较低的碳水化合物摄入。

youdao

Louisiana is also one of the world's largest producers of what some call "the most important fish you've never heard of": menhaden.

VOA: special.2010.05.04

So out of kind of this empowerment you created what is now one of the most important interfaith groups in America.

所以，从这种震撼和激励中,您创立了目前美国最重要的,一个跨信仰组织。

普林斯顿公开课 - 人性课程节选

What do you think is the most important thing to teach students who learn English as a second language?

你觉得要教那些以英语为第二语言的学生，最重要的是什么？

教英语 - SpeakingMax英语口语达人

Despite the failures you've experienced, the most important thing you can do is not give up.

CNN: My son hears suicidal voices. What can I do?

You can be a proud mom without having that be the most important thing you want people to know about you.

FORBES: Are Kids a Career Kiss of Death?

The development of human capital is the most important challenge you have, and we pledge to support you in the process of transition.

UNESCO: EDUCATION FIRST