...： 氯化镉；人肝癌细胞；细胞增殖核抗原；金属硫蛋白 [gap=2179]Keywords : cadmium chloride;human hepatocarcinoma cells;proliferating cell nuclear antigen;metallothionein ..
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Objective: To investigate the anti-proliferation effect and apoptosis-inducing activity of synthetic saponin in Solanum indicum L. on human hepatocarcinoma BEL-7402 cells.
目的：探讨合成紫花茄皂苷对BEL-7402细胞的增殖抑制及凋亡诱导作用。
Matrine inhibits the proliferation of the cells by blocking the hepatocarcinoma cell cycle to G0-G1 phase, and develops its anti-hepatocarcinoma function by inducing human BEL-7402 cells apoptosis.
苦参碱可能是通过将人肝癌细胞周期阻滞在G0～G1期，抑制其增殖，通过诱导人肝癌细胞发生凋亡等，发挥其抗肝癌作用。
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