In the 10 ~ 12 weeks, a more disordered structure of hepatic lobule, early cirrhosis.
建模第10 ~ 12周，肝小叶结构更加紊乱，出现早期肝硬化迹象。
HBV can usually escape early and late immune response leading to chronic liver disease-chronic hepatitis B, liver cirrhosis, liver failure and hepatic cellular carcinoma.
HBV通常可以逃避早期和晚期免疫应答导致慢性肝脏疾病——慢性乙型肝炎、乙肝后肝硬化、肝衰竭、肝癌。
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