They have joined the job market at the worst possible time.

他们在一个最遭糕不过的时候进入了职场。

《柯林斯英汉双解大词典》

Their retirement savings and home values fell sharply at the worst possible time: just before they needed to cash out.

他们的退休储蓄和房屋价值在最糟糕的时机急剧下跌：就在他们需要套现之前。

youdao

As usual, they were selling at the worst possible time.

像往常一样，他们在最糟的情况下卖出。

youdao

Mister Kan also said the crisis at the Fukushima Daiichi nuclear power center is the worst Japan has ever faced.

VOA: special.2011.03.19

And I'll also remind you, and we're going to see this in the next example, we talked about looking at the worst case behavior. In these cases there's no best case worst case, it's just doing one computation.

我还要提醒大家的就是，我们也会在下一个例子里发现者一点，我们谈到了要去考虑最坏的情况,在下面这些例子里,没有好情况坏情况之分，就只是一次运算。

麻省理工公开课 - 计算机科学及编程导论课程节选

So the gentleman here was looking at the worst case scenario, and the woman here was looking at the best case scenario.

刚才的小伙子看的是最坏的情况,而这位女士看的是最好的情况

耶鲁公开课 - 博弈论课程节选

Hurricane Sandy struck one of the biggest car-buying regions at the worst time of the month possible.

FORBES: Hurricane Sandy's Lost October Car Sales Will Return

Others adjusted their portfolios at the worst possible time, selling stocks when they should have been buying.

FORBES: The Lost Decade Was A Golden Age If You Rebalanced

Joan Herbig got the promotion of a lifetime at the worst possible time.

FORBES: Survivor