Adam describes his feeling that with hospitals, every step along the way, the doors would keep opening.

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She has been confused at every step along the way about what this motion is supposed to do.

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"We followed individuals from the time of HIV infection to the time they generated broadly neutralizing antibodies, and mapped and isolated the virus at every step along the way so we now don't have to guess any more about what induced those antibodies, " he says.

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Reluctantly but pragmatically, Arnold goes along, grouching and grizzling every step of the way.

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