In addition to the familiar duplex DNA, certain G-rich DNA sequences can fold into a variety of four-stranded structures, which are called G-quadruplexes.
富含鸟嘌呤碱基的DNA序列能够通过鸟嘌呤环的互联作用形成四链螺旋结构，这种结构被称为G-四链体。
Positive charges and substituent size in TPM dyes may be two important factors in influencing the binding stability of the dyes and G-quadruplexes.
此外，还发现TPM染料所带的正电荷数以及取代基的体积是影响染料和G-四链体结合稳定性的两个重要因素。
The results show that the fluorescence spectra of four TPM dyes can be used to discriminate intramolecular G-quadruplexes from intermolecular G-quadruplexes, single-and double-stranded DNAs.
结果表明四种TPM染料的荧光光谱可用于区分分子内G-四链体和分子间G-四链体、单链和双链DNA。
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