Most older antimalarials have been rendered useless by drug resistance.

耐药性已使多数较陈旧的抗疟药物失去效用。

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Unlike previous antimalarials that have been rendered useless in many regions due to drug resistance, Artemisinin Combination Therapies (ACTs) are now recommended.

与在许多地区由于耐药性而无效的以前各种抗疟药不同，目前推荐使用以菁蒿素为基础的联合治疗药物。

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Insect resistance to Bt would do irreparable harm, not just to genetically modified crops, but to organic crops as well, because Bt sprays would be rendered useless.

而Bt抗性也会产生不可取代的危害，不仅是对于基因改良作物，还有那些需要用Bt喷雾来抗虫的作物。

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