AIM: to construct plasmid vector of RNA interference specific for matrix metalloproteinases (MMP) -9 and observe the silencing effect on gene expression of MMP-9 in macrophage of mice.

目的：构建基质金属蛋白酶9靶向的RNA干扰质粒载体，观察其对小鼠巨噬细胞基质金属蛋白酶9基因表达的沉默作用。

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Objective Recently, a naturally occurring gene silencing mechanism triggered by double-stranded RNA (dsRNA), RNA interference (RNAi), has been described in a number of species including Drosophila.

目的近年来，双链rna介导的基因沉默(RNA干扰)已在许多动植物中发现，并成为研究基因功能的强有力的工具。

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Allerca initially planned to use the gene-silencing technique called RNA interference to quieten the gene that encodes Feld1, the protein that affects allergy sufferers.

Allerca公司最初是计划用基因静默技术（RNAi）来沉默编码Feld1（导致过敏性反应的蛋白）的基因。

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Now a similar sea change may be afoot, thanks to a new technology called RNA interference, or RNAi, which allows scientists to stop a disease by silencing a particular gene.

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