Objective To solve the problem of non-inferiority test by adjusting central effect in multicenter trials.

目的解决校正中心效应的非劣性检验的问题。

youdao

Phase III studies are multicenter trials on large patient groups designed to be the definitive assessment of a drug's effectiveness.

三期研究是为最终评估药物有效性而在大批病人中进行的试验。

youdao

Benefit relative to placebo has been demonstrated in two large multicenter trials, with low doses (100 or 150 mg) having been shown to have therapeutic efficacy.

效益与使用安慰剂已经展示了两个大型的多中心临床试验(100或150毫克)低剂量后，被证明具有疗效。

youdao

Clinical results from any specialized cancer center are typically very difficult to reproduce in broader multicenter trials, in part because there may be differences, whether measured or unmeasured, between those presenting at renowned centers of excellence and those who remain close to home.

FORBES: Is IBM's Watson in Jeopardy? This Oncologist Thinks So!