Choosing the suitable drugs and dosages according to cytochrome P450 and drug metabolism would improve the pharmacotherapy efficacy and reduce the adverse drug reaction and toxic effect of drugs.

根据细胞色素P 450和药物的生物转化来选择合适的药物及合适的剂量将有助于最大程度地提高药物治疗效应，同时减少药物不良反应和毒副作用。

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Conclusion: SMI is an effective drug for treatment of diaphragmatic fatigue in children with less adverse effect, and worthwhile for spreading in clinical practice.

结论：参麦注射液是一种有效的治疗儿童膈肌疲劳的药物，且副作用小，值得临床推广。

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Compared with chlorpromazine, clonidine was less effective in producing sedation, however, it produced anti-depression effect with fewer adverse drug reactions.

氯丙嗪控制兴奋躁动优于可乐定；可乐定的不良反应明显少于氯丙嗪，而且具有一定的抗抑郁作用。

youdao

First, the active drug would have to be present in the food at sufficient levels to exert an adverse effect via direct toxicity or allergy.

FORBES: Food Fight