Driven to distraction, he murdered the woman who jilted him.

盛怒之下，他谋杀了抛弃他的那个女人。

《柯林斯英汉双解大词典》

He was driven to distraction by the pain in his shoulder.

肩膀上的痛令他备受困扰。

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For parents driven to distraction by their children's little white lies, here is the good news.

父母们面对孩子小谎言的时侯都会抓狂，但现在震惊的好消息来了。

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Dr White reckons that the residents of Cowboy Wash may have fallen victim to starving raiders, driven to distraction by failed harvests.

ECONOMIST: Anthropophagy

Israel's economy, though not without the odd tremor, has boomed in comparison with those of its floundering Arab neighbours, where governments have been driven to distraction or overthrown amid the turbulence of the Arab spring.

ECONOMIST: Israel and Palestine