Let your doctor know if you notice a dramatic decrease or change in frequency.

如果你意识到频率急剧的增加或改变就需要让你的医生知道。

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Dramatic decrease in the global disease burden: from 5.2 million in 1985 to 805 000 in 1995 to 753 000 at the end of 1999 to 213 036 cases at the end of 2008.

全球疾病负担大量减少：从1985年的520万例减少到1995年的80.5万例，1999年底为75.3万例，2008年底为213 036例。

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Looking at vehicles and fuel in a holistic manner has led to regulations calling for a dramatic decrease in the sulfur content of gasoline and diesel fuel.

从车辆和燃料的综合考虑出发，已经有多项旨在大幅度减少汽油和柴油硫含量的法规出台。

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"One of the things we've seen is a dramatic decrease in purebreds, " Herzog said.

CNN: When nothing is too fancy for Fido

Meanwhile, the ICO is chasing spammers, leading to a "dramatic decrease" in activity, says Wigmore.

BBC: PPI: The unintended consequences of a scandal

However, the dramatic decrease of demand in the last few years has become far too great a burden to be covered by corporate efforts.

ENGADGET: Fujifilm sees which way wind is blowing, ends production of cinema film