Abandoned by her husband, Flo shares her home with her two children, Millie (Madeleine Martin) and Madge (Maggie Grace), and a boarder, Rosemary (Elizabeth Marvel).
They also bear witness to the peculiar sexual arrangements in the house, in which Roosevelt (Bill Murray), carried from room to room by a servant, appears to be having relations with his secretary, Missy LeHand (Elizabeth Marvel), and also with his distant cousin Daisy Suckley (Laura Linney).