Although no cure has been discovered yet, Dr.Sabbagh says significant progress has been made over the past 15 years.

VOA: standard.2009.12.04

which is significant is that lot got reading about those websites but almost no one saw them, because they were removed from public view within a few minutes after the shooting took place in the high school.

重要的是,很多人都知道了他们的网站,但没有几个人真正上过这个网站，因为这一事实被掩盖于公众眼前,不过几分钟的时间在枪击案,发生在高中里。

麻省理工公开课 - 媒体、教育、市场课程节选

As saying in a television interview, this is Allen Greenspan while I was aware of a lot of these practices, these lending, were going on, I had no notion of how significant they had become until very late.

这是他接受采访时说的，艾伦，格林斯潘说,我之前i就知道有很多不规范行为，：，“,这些借款，但我不知道问题的严重性,直到很晚。

斯坦福公开课 - 经济学课程节选

"Otherwise you have the really problematic bottom line, which is that the Central Intelligence Agency is running a program that is killing significant numbers of people and there is absolutely no accountability in terms of the relevant international laws,".

VOA: standard.2009.10.27