Objective To summarize the status of tumor stem cells study in solid tumors.
目的介绍肿瘤干细胞在实体肿瘤中的研究进展。
"Tumor stem cells are cells that can initiate a whole tumor," Ince explained.
“肿瘤干细胞是指启动整个肿瘤生长的细胞，”Ince解释。
Tumor metastasis is closely related to metastasis and homing of tumor stem cells.
肿瘤转移与肿瘤干细胞的转移和归巢行为密切相关。
If the tumor stem cells have not been cleared, then relapse and metastasis may be inevitable.
肿瘤干细胞是肿瘤转移和复发的根源。
"Cataloging brain tumor stem cells will be an enormous tool for patient diagnosis, " explains Dr.
研究人员表示，对脑瘤干细胞的分类目录将成为患者诊断的强大工具。
Importantly, a significant over-expression of these molecules were found in the brain tumor stem cells.
但重要的是，脑肿瘤干细胞中这些分子呈现显著的过表达。
Though brain tumor stem cells are low proportion in tumor tissue, they are the key for maintaining malignance.
但其在肿瘤组织中所占的比例很低，却是肿瘤保持恶性特征的关键所在。
This article reviews the relationship and regulatory mechanism between normal stem cells and epithelial tumor stem cells.
现综述近年来有关上皮干细胞和肿瘤发生的关系及其调控机制方面的研究进展。
Taking radiotherapy of tumor stem cells as a contact point, strategy designed by radiobiology can essentially solve this problem.
将肿瘤干细胞作为放射治疗的切入点，针对其放射生物学行为制订对策，才能从根本上解决问题。
Now researchers have shown that this extraordinary radiation-resistance among tumor stem cells can be dramatically lowered by heating them up.
现在研究人员发现肿瘤干细胞在加热以后其惊人的抗辐射能力急剧下降。
"Until now, most of the drug testing had been done on standard tumor cell lines that only have very few tumor stem cells in them," Ince explained.
“直到目前，大部分药物实验只在标准的肿瘤细胞系中测试，而这些细胞系很少含有肿瘤干细胞，”Ince解释到。
Challenges have been proposed to the classical theory of origin cells of glioma, since the successful researches on neural stem cells and tumor stem cells.
神经干细胞和胶质瘤干细胞的研究成功，对早有定论的胶质瘤起源细胞学说发出了挑战。
So it is generally assumed that tumor cells are derived from normal stem cells, more work is needed to identify and characterize epithelial tumor stem cells.
所以，人们认为肿瘤多起源于正常干细胞。然而，目前研究中关于上皮肿瘤干细胞及其与正常上皮干细胞的关系了解甚少。
BACKGROUND: There may be tumor stem cells during metastasis and recurrence of liver cancer. The number of tumor stem cells is very few, so it is difficult to be identified.
背景：肝癌的转移复发被认为可能存在有肿瘤干细胞，后者在肿瘤细胞中数目极少，使得临床鉴别存在一定困难。
Objective To pursue the changes of cell morphology, expression of differentiation related markers, and proliferation cycles of brain tumor stem cells (BTSCs) after differentiation in vitro.
目的探讨脑肿瘤干细胞(BTSC)在体外分化过程中的细胞形态、分化相关标志物表达和增殖动力学变化，为进一步研究BTSC分化走向提供实验依据。
There is overwhelming evidence that the tumor clone including brain tumor is heterogeneous with respect to both morphology and function, which indicates differentiation potential of tumor stem cells.
大量事实表明，包括脑肿瘤在内，所有肿瘤细胞群落之间在形态和功能上存在很大差异，其异质性与肿瘤干细胞的分化潜能有关。
Chemotherapy might effectively kill an entire tumor, but cancer stem cells might evade the drugs and cause a relapse of the cancer years later.
化学疗法也许能有效地杀死整个肿瘤，但是癌症干细胞可能会躲开药物，在几年后导致癌症的复发。
Some experts believe that drugs that kill most tumor cells do not affect cancer stem cells, which can regenerate the tumor.
一些专家认为能杀死大多数癌细胞的药物并不会影响癌干细胞，而干细胞仍能生出肿瘤。
A recent University of Michigan study on mice found that sulforaphane also targets cancer stem cells-those that aid in tumor growth.
密歇根州立大学最近一个基于小白鼠的研究发现，萝卜硫素也攻击癌症干细胞——该干细胞是肿瘤生长的帮凶。
The concept of cancer stem cells may have profound implications for our understanding of tumor biology and for the design of novel treatments targeted toward these cells.
肿瘤干细胞的概念对于我们理解肿瘤生物学和构思针对这类细胞的靶向治疗来说，可能有着更加深远的意义。
The theory of cancer stem cell proposes that the tumor tissue has its own cancer stem cells in it and regards cancer stem cell as the key to regeneration, metastasis and recurrence.
肿瘤干细胞学说认为，肿瘤组织中也存在少量具有干细胞性质的肿瘤干细胞，肿瘤干细胞是肿瘤发生、转移和复发的关键。
Unlike tumor cells, the transplanted stem cells achieved homeostasis, growing to a stable, constant level and ceasing replication.
不同的肿瘤细胞，移植的干细胞达到平衡，增长到一个稳定的，恒定的水平，并停止复制。
The purported cancer stem cells produced a diverse mixture of cells, some of which are not cancerous, that reflected an actual human pancreatic tumor, she said.
所谓的癌症干细胞产生了不同类型的细胞群，其中一些是非成瘤性的，这也和人类胰腺癌肿瘤相类似。
In lab tests using mice with breast cancer, researchers found that the drug combination suppressed the cancer stem cells thought to drive tumor progression.
实验室中以患乳腺癌的老鼠为试验对象，研究者发现联合用药可以抑制癌症干细胞，而癌症干细胞是肿瘤扩增的驱动因素。
It is a special kind of stem cells with highly proliferative and self-regenerative cap ability to maintain its number stable and generate tumor.
肿瘤干细胞是一种特殊类型的干细胞，具备高度增殖能力与自我更新能力，其结果是维持肿瘤干细胞数目稳定并产生肿瘤。
It is a special kind of stem cells with highly proliferative and self-regenerative cap ability to maintain its number stable and generate tumor.
肿瘤干细胞是一种特殊类型的干细胞，具备高度增殖能力与自我更新能力，其结果是维持肿瘤干细胞数目稳定并产生肿瘤。
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