These two tRNA synthetases link protein synthesis to a major cell signaling pathway in the given mammalian cells.
在哺乳动物细胞中，蛋白质的生物合成途径与细胞信号转导途径紧密相连。
Interference on key components in this signaling pathway may lead to marked inhibition of cell growth, which implies a new promising target for targeted therapies for ovarian cancers.
干预该信号通路的关键组分显著抑制细胞生长，为卵巢癌的靶向治疗提供了新的有价值的干预靶点。
AIM: to investigate the influence of TG-interacting factor (TGIF) on the retinoid signaling pathway in gastric cancer cell line SGC-7901 in vitro.
目的：探讨TG -相互作用因子(TGIF)对胃癌SGC- 7901细胞株中维甲酸信号通路的影响。
Conclusion: The conventional fractioned radiotherapy can activate cell mediated immunity of CD8+ T and NK cells, but inhibit the differentiation of T cells and NK cells signaling transduction pathway.
结论：放疗能部分激活CD8+T及NK细胞介导的杀伤免疫，同时抑制T细胞和NK细胞的分化及其信号传导通路。
Suppressors of cytokine signaling (SOCS) associates with receptor-mediated signal transduction pathway, which can regulate cell proliferation, growth, differentiation and inflammation et al.
细胞因子信号转导抑制蛋白(SOCS)通过与受体介导的信号转导，调节细胞增殖、生长、分化及炎症发生等。
To investigate the change of mitogen activated protein kinase(MAPK) signaling pathway during prostate cancer progression, and therefore to explore its role on cell proliferation.
目的：研究前列腺癌进展中细胞丝裂原活化蛋白激酶（MAPK）信号通路的变化，探讨阻断此通路对前列腺癌细胞增殖的影响。
Conclusion: Our results suggest that long-term stimulus with the low-concentration ethanol-induced gastric mucosal cell proliferation is related with BMK1 signaling pathway via ROS production.
结论：慢性饮酒刺激胃黏膜底腺干细胞的增殖可能与酒精引起活性氧（ROS）增多有关，同时本研究还第1次发现慢性饮酒诱导胃底腺干细胞增殖是由BMK1所介导。
Conclusion: Our results suggest that long-term stimulus with the low-concentration ethanol-induced gastric mucosal cell proliferation is related with BMK1 signaling pathway via ROS production.
结论：慢性饮酒刺激胃黏膜底腺干细胞的增殖可能与酒精引起活性氧（ROS）增多有关，同时本研究还第1次发现慢性饮酒诱导胃底腺干细胞增殖是由BMK1所介导。
应用推荐