Phase II trials with an antisense oligonucleotide against HSP-27 in CRPC are underway.
以HSP-27为靶点的反义寡核甘酸正处于第二期临床试验中。
Objective: to screen the high performance, specific and nontoxic anti HBV antisense oligonucleotide fragment.
目的：筛选出高效特异而无毒的抗hbv反义寡核苷酸片段。
CONCLUSION: EAAC1 antisense oligonucleotide has the neuroprotective effect against acute cerebral ischemia injury.
结论：EAAC 1反义寡核苷酸对急性脑缺血损伤有神经保护作用。
Objective: To study the antisense oligonucleotide mediated inhibition on telomerase activity and cell proliferation of GBC-SD cell.
目的：探讨反义寡核苷酸对胆囊癌细胞端粒酶活性的影响及对胆囊癌细胞生长增殖的作用。
To study the inhibitory effect of bcl-2 antisense oligonucleotide (ASODN) combined with radiation on lung carcinoma cells NCI-H446.
研究Bcl - 2反义寡核苷酸联合照射对肺癌细胞的抑制作用。
Objective To evaluate the therapeutic effect of antisense oligonucleotide targeting Survivin in the treatment of tumor-bearing nude mice.
目的评价生存素反义寡核苷酸在荷肝癌小鼠中的治疗作用。
Objective to investigate the effects of keratinocyte growth factor (KGF) and KGF receptor (KGFR) antisense oligonucleotide (ASODN) on cell cycle and apoptosis of HaCat cells.
目的研究角质形成细胞生长因子(KGF)及其受体(KGFR)反义寡核苷酸对KGF介导的细胞周期和凋亡变化的抑制作用。
Methods: After incubated with BHRF1 antisense oligonucleotide, BHRF1 CNE2 cells were treated with camptothecin, and tested for the alterations of proliferative ability and apoptotic index.
方法：检测反义阻断BHRF1表达后BHRF 1 -CNE2细胞在喜树碱作用下增殖能力和凋亡指数的变化。
Methods: After incubated with BHRF1 antisense oligonucleotide, BHRF1 CNE2 cells were treated with camptothecin, and tested for the alterations of proliferative ability and apoptotic index.
方法：检测反义阻断BHRF1表达后BHRF 1 -CNE2细胞在喜树碱作用下增殖能力和凋亡指数的变化。
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