But the second saddest sight in sports is the great athlete who doesn't know his or her career is over.
One the most well-known retinal implants in the world today is the Argus2 from Second Sight, which is a silicon-based prothesis.
The Greeks continued their shoot-on-sight policy as the second-half unfolded and Karagounis brought out the best in McGregor again with a powerful drive.
We were greeted by the sight of a second cruise ship that dropped off supplies and amazingly we were able to pick up a cell phone signal from the other ship.
Only the omnipresent Gardner had a real sight on goal for Villa in the second half when he arrived late to latch on to a Wayne Routledge cross and unleash a shot that was deflected wide.
Most major TV manufacturers had, for the second year in a row, a laser-sight focus on the technology.
But it was Boro who initially threatened in the second period when Viduka bamboozled Brown allowing the Australian a clear sight of goal.
BBC: SPORT | Football | Premiership | Man Utd 1-1 Middlesbrough
The second consequence has been the fraying of an empire, and the sight of its emperor under siege.
Boro began the second half with much greater purpose and should have put the game out of sight.
Those in the US suffering from blindness due to retinis pigmentosa (RP) will now be able to regain some vision bionically for the first time ever, thanks to Second Sight's Argus II retinal prosthesis.
Second Sight Medical Products developed the world's first working bionic eye, which could soon be available in the US, and fashion company Machina produced the world's first jacket to combine a MIDI controller with motion sensors -- essentially, it's a jacket that turns your body into a synthesizer.
The device, called the Argus II Retinal Prosthesis System and made by Second Sight Medical Products of Sylmar, Calif.
Second Sight is backed in part by the billionaire medical device investor Al Mann, who is its chairman, and by the legendary device inventor and venture capitalist Thomas Forgarty.
The Blues were also boosted by the sight of inspirational number eight Xavier Rush returning to action after injury in the second half, as the New Zealander came off the bench for Molitika.
Second Sight will be actively adding sites to make the therapy more readily available and encourages interested facilities and patients to contact them.
ENGADGET: FDA clears Argus II 'bionic eye' for sale in the US (video)
Dr. Robert Greenberg, Second Sight's chief executive, told the New York Times that eventually, the company would like to implant the electrodes directly into the brain's cortex to treat blindness from all causes.
Argus II is set to become available later this year in U.S. clinical centers, and Second Sight said it would be adding sites to make the therapy more readily available.
Patients report the biggest gains are in improved orientation and mobility, said Robert Greenberg, Second Sight's CEO, who also is a medical doctor.
Second Sight believes that U.S. insurers will likely cover the cost of the device for patients who may not have other ways of treating their vision loss.
With the Deepwater Horizon oil spill now moving into its second month and no immediate end in sight, BP is ( see WSJ story today) attempting to throw Transocean under the bus as responsible for the disaster.
At first sight this seems strange, since the venture-capital industry in Britain is second only to America's in scale.
ECONOMIST: The fund may be new but the idea is surprisingly old
Divers and adventurers will salivate at the sight of the translucent waters and massive coral arrays of the Mesoamerican Reef - the second-largest barrier reef in the world.
Second-placed Investec Royal finished almost four hours later, having been becalmed in sight of the docks.
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