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  • In which case, how quickly do they converge on a final protein structure?

    ECONOMIST: REPORT: COMPUTING: Big Blue’s big bet | The

  • "I happen to be an expert in protein structure and how viruses enter cells and how to stop that, " Kim says.

    FORBES: Peter Kim To Head Merck's Labs

  • This finding is in line with modern thinking that a lot of evolutionary change is connected with regulatory elements rather than actual protein structure.

    ECONOMIST: Evolution

  • Dr Sander began by assessing how well protein-structure prediction has worked until now.

    ECONOMIST: Structural genomics

  • Dr Dobson and Dr Serrano have now shown that mutations, used judiciously, can actually suppress it—and that they can do so without changing the protein's structure and function.

    ECONOMIST: Folding stuff

  • Working with the geneticists' favourite animal, the fruit fly Drosophila, Dr Gibson has pinpointed a series of so-called cryptic variations that have no effect on a protein's structure, but can nevertheless, if the circumstances are right, have a significant effect on the individual they belong to.

    ECONOMIST: Genetics gets more complicated

  • Merck has invested hundreds of millions of dollars in using yeast for protein production, but Merck's yeast technology does not allow it to control the type of sugar structure on the protein.

    FORBES: Pharma's Little Helper

  • Scientists had attempted to model a 3D structure of a protein associated with the HIV virus for 15 years and failed.

    FORBES: Practical Implications

  • Trifluoroethanol is known to open up the pretzel-shaped structure of a protein.

    ECONOMIST: Folding stuff

  • After scientists repeatedly failed to piece together the structure of a protein-cutting enzyme from an AIDS-like virus, they challenged the gamers to produce an accurate model of the enzyme — which they did in three weeks.

    FORBES: How Cloud Computing Can Boost Developing Nations

  • But studying the structure of the antibody and the protein on the flu virus that it targets could make it that much more likely for a universal vaccine to be developed.

    FORBES: One Step Closer to a Universal Flu Vaccine?

  • Since knowing the structure of one member of a protein family lets researchers guess what others will look like, the most efficient strategy for choosing protein targets should cover as wide a diversity as possible.

    ECONOMIST: Structural genomics: Strategic thinking | The

  • Instead, differences in composition between warm-water and cold-water ion channels were the result of a phenomenon called RNA editing, in which special enzymes alter the structure of the RNA messenger, and thus of the final protein.

    ECONOMIST: A hitherto-unknown way to evolve

  • Players are presented with a protein and given the task of finding its most energy-efficient shape by fiddling with its structure.

    ECONOMIST: What video-game technology can do in the real world

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