Not surprisingly, Fortune 500 companies are building mindfulness into leadership development programs with profound effects.
Facing these chronic problems head on would have profound effects, lasting long beyond delivery.
As every awkward adolescent or expectant mother knows, sex hormones can have profound effects on the body.
The most profound effects, however, have been in the perceptions of women in society and among themselves.
There are quite a few Supreme Court decisions that have had profound effects.
It is important to consider inflation because even mild rates of inflation have profound effects over long periods of time.
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The hardware evolution that is tablet computing is already having profound effects on social computing, and it was pretty cool that a little molding company in Ohio woke us up to that.
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So we started to learn how to go deeper into problem solving, to provide capacity building tools to our community partners, and to educate policymakers whose decisions have profound effects on the lives of the people we serve.
The long-term impact on the nuclear power industry is yet to be seen, but what is clear is that natural disasters like the earthquake and tsunami in Japan have profound effects on governments and on businesses, directly or indirectly.
Outside these core areas, and at lower altitudes, the culture and farming practices of mountain people can have profound effects on local ecology, making the effects of climate change difficult to distinguish from those directly due to human activities.
Most children who are born with my disease, toxoplasmosis, have profound side-effects that can include organ failure, blindness, and intellectual disabilities.
To harm a child sexually has profound and lasting effects and many argue that the law does not go far enough in punishing offenders.
Just across the border, in Canada, the effects were just as profound.
Most important, this approach buys much-needed time to consider the ill effects of any legislation that might be pushed through quickly and later found to have profound and devastating consequences.
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The knock-on effects mean that now, aged nine, she has a complex range of medical needs and profound learning difficulties.
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