• "When I started in 2001, no one was interested in Muckle-Wells, " recalls UCSF dermatologist Kieron Leslie.

    FORBES: The Ultimate Targeted Therapy

  • Two months later Fishman hired rheumatologist Wright, who proposed testing Novartis' own antibody in Muckle-Wells.

    FORBES: Magazine Article

  • Regeneron tested its own drug in 47 Muckle-Wells patients, and it helped all of them.

    FORBES: Magazine Article

  • Regeneron's drug is given weekly and could be approved for Muckle-Wells and its milder cousin this year.

    FORBES: The Ultimate Targeted Therapy

  • This month Novartis begins a follow-up trial in up to 40 Muckle-Wells patients.

    FORBES: Magazine Article

  • Hoffman at UC, San Diego in 2001 pinpointed the gene mutation that causes Muckle-Wells and the inherited overreaction to drafts.

    FORBES: The Ultimate Targeted Therapy

  • Souther's disorder is the milder cousin of Muckle-Wells syndrome, and the causes of both were unknown until a a few years ago.

    FORBES: The Ultimate Targeted Therapy

  • In 2003 British researchers tested Amgen's interleukin-blocking rheumatoid arthritis drug, Kineret, in two Muckle-Wells patients who had not been helped by other drugs.

    FORBES: The Ultimate Targeted Therapy

  • Wright proposed testing the drug in patients with a disease so rare that some of his superiors had never heard of it: Muckle-Wells syndrome.

    FORBES: Magazine Article

  • Novartis' promising Muckle-Wells drug--its antibody against interleukin-1, which it first aimed at arthritis--was one of the first drugs to benefit from Fishman's new testing regimen.

    FORBES: Magazine Article

  • James Muckle, who manages a 32-unit apartment building in Sebastopol, Calif.

    FORBES: On The Cover/Top Stories

  • Yancopoulos, Regeneron's chief scientist, says he heard about the possibilities in treating Muckle-Wells and made an "impassioned plea" to Novartis to test Regeneron's drug for that malady.

    FORBES: Big Bucks

  • And though the company earlier had spurned a biotech firm's proposal to jointly study Muckle-Wells, Wright convinced his bosses that the obscure disorder was the perfect test-bed for the new compound.

    FORBES: Magazine Article

$firstVoiceSent
- 来自原声例句
小调查
请问您想要如何调整此模块?

感谢您的反馈,我们会尽快进行适当修改!
进来说说原因吧 确定
小调查
请问您想要如何调整此模块?

感谢您的反馈,我们会尽快进行适当修改!
进来说说原因吧 确定