The runner, who died of cardiac failure caused by extreme exertion, would call Ms Munton on long training stints.

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Considering that Pol Pot was about 73 and had a history of ill health -- in recent years, he suffered a minor stroke and had cardiac problems -- a heart failure is perfectly feasible.

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Even after its regulatory problems, the company is a leader in the field of implantable cardiac defibrillators, devices that are implanted in heart-failure patients.

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Jarque's death comes two years after that of Sevilla and Spain defender Antonio Puerta, who suffered multiple organ failure in hospital, three days after a cardiac arrest during a league match against Getafe.

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Anyone quick to dismiss this potential problem need only think back on our humbling recent experiences with ICD failures to recognize that the late manifestation of an unanticipated failure mechanism is a fact of reality in cardiac rhythm devices.

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Initially, Medtronic and Genzyme will work to complete an ongoing 300-patient trial in Europe testing whether injecting skeletal myoblasts into damaged areas of the heart during cardiac bypass surgery helps improve symptoms and reduces hospitalizations in heart failure patients.

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Affected males with this progressive muscular disease become wheelchair bound before 13 years of age, are ventilator dependent in their late teens to early 20s due to respiratory failure, with death in their late 20s to 30s due to cardiac or pulmonary problems.

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It was the latest high-profile case of a football player collapsing from heart failure on the pitch, coming less than a month after Bolton midfielder Fabrice Muamba suffered cardiac arrest during a game in England.

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